• Phosphohexose Isomerase (PHI) is an enzyme that regulates anaerobic metabolism. This enzyme is an Autocrine Motility Factor (AMF), and is one of the main cellular causes of malignancy, i.e. cell migration. It also plays a most important role in cells becoming cancerous by turning them into sugar users. It is responsible for channeling the cells into low oxygen glycolysis ie. fermentation. Because cancer cells favor anaerobic conditions PHI is an excellent marker. It can be elevated in a developing cancer, existing cancer, or in an acute heart, liver, muscle disease, or acute viral infection. Examples of these acute conditions are myocardial infarction, hepatitis, aids, and traumatic muscle injury. If an acute condition can be ruled out, cancer may be the cause of the elevated result and the 10-12 year cancer developmental period's time may be ticking. Normal results are <43.0 (less than 43), however, in an established malignancy a change even within the normal range could be significant. Take notice that this enzyme is an AMF (autocrine motility factor), causing malignant cancer spread.

|  Blood Tests  |  Home  |  About Our Doctor  |  Contact Us  |